Growfx®

An advancement in regenerative therapy utilizing connective tissue matrix, GrowFX® is intended for homologous use to fill space and provide support. 

Connective Tissue Matrices function as a filler and support to voids throughout the human body1. 

Connective tissue matrix consists of fibers, proteoglycans, and glycoproteins. The specific type of these macromolecules are determined by the body area the tissue is native to1. 

Amnio Technology’s proprietary AdvanTek ® process preserves the original relevant characteristics of the connective tissue matrix. The process allows those relevant characteristics of the connective tissue matrix to be delivered in a flowable form that meets the various clinical needs of tissue filling and support. 

WHERE DO THE TISSUES COME FROM? 

GrowFX® product donor tissues are recovered with sterile equipment, using one of the safest recovery techniques to minimize contamination. 

Connective tissue matrix are procured in the US, through a network of qualified and trained recovery partners, following stringent screening and recovery protocols. All products are processed aseptically in accordance with current Good Tissue Practice (cGTP) and current Good Manufacturing Practice (cGMP) standards. 

Donors are prescreened through an intensive and complete medical review. Communicable disease testing is performed by a Food and Drug Administration (FDA) registered and Clinical Laboratory Improvement Amendments (CLIA) laboratory. A Donor blood sample is taken prior to or at the time of recovery and tested for HBsAg, HBcAb, HCVAb, HIV1/2 Ab, HCV NAT, HIV NAT, HBV NAT, RPR/STS, HTLVI/II, and WNV. 

Components found in GrowFX ®
include: 

Amniotic tissue and membrane are known to contain collagen substrates, growth factors and extracellular matrix proteins all recognized as part of the complex wound healing process. Amnio Technology products are derived exclusively from the amnion and are chorion-free. Key natural elements found in placental tissues:

• Growth Factors
• Cytokines
• Amino Acids
• Extracellular Matrix Proteins
• Hyaluronic Acid

• Fibroblast Growth Factor (FGF)
   
• Epidermal Growth Factor (EGF)
   
• Platelet Derived Growth Factor
  (PDGF) A& B
   
• Vascular Endothelial Growth Factor
  (VEGF)
   
• Transforming Growth Factor -beta 

           (TGF-β) 

• Hyaluronic Acid (HA)
   
• Proteoglycans
   
• Glycoproteins
   
• Soluble ECM Proteins
   

• Available in multiple volumes
   
• May be administered topically or
  implanted, based on clinical preference
   
• May be applied directly to the area of interest by implantation through a 22 gauge or larger needle
   
• Terminally sterilized using E-Beam Irradiation
   
• Stored Long-term at room temperature (15-30° C)
   

Product Volumes

• GFX-050025  GrowFX®   0.25 cc 
• GFX-050050  GrowFX®   0.50 cc
• GFX-050100  GrowFX®   1.00 cc
• GFX-050200  GrowFX®   2.00 cc